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KMID : 0605619980050010017
Journal of Korean Society of Biological Psychiatry
1998 Volume.5 No. 1 p.17 ~ p.33
Therapeutic Appilication of Molecular Genetics in Psychiatry
À̹μö/Min Soo Lee
Abstract
Advances in molecular biology contribute to the understanding genetic mechanism of
psychiatric disorders. They have renewed hope for the discovery of disease relevant
gene.
However, the results somewhat confused. And we will wait for a long time for the
application of gene therapy in schizophrenia. Fortunately we could classified the
schizophrenia with genotypes of dopamine and serotonin receptors. It is expected that
this genetic classification could provide key strategy for the therapeutic application in
biological treatment for schizophrenia.
The purpose of this article is to call attention of the institute participants to linkage.
association. mRNA expression. genotypic classification and to the need for more
systemic research. The author summarized the modified methods which were done in his
laboratory in appendix.
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